Located at Design Miami from 1 to 5 December, the ON/ installation will be a precisely scaled sculpture of the electric concept car made from steel wire and embedded with LED lights.
It will explore Lexus' "electrified, carbon-neutral vision for the future", according to the brand.
"The car glows and is suspended just above the ground, a vision of a more sustainable future coming into focus," Lexus said.
Installation can be customised by people around the world
Ahead of the unveiling of the sculpture, Lexus and Barnes have created an interactive virtual model of the installation alongside the physical display.
Using the digital tool above, anyone around the world can create their own lighting scheme for the display, altering the colours of the car, as well as the surrounding swings and furniture.
Barnes and his team will select some of these user-generated designs to display at Design Miami in the real-world installation when it opens to the public tomorrow.
"We're excited to partner with Germane Barnes and the University of Miami for this year's edition of Design Miami, and looking forward to seeing their vision for a more human-centric and carbon-neutral future come to life," said Brian Bolain, Lexus' global head of marketing.
"The LF-Z Electrified represents the future of the field for us, paving the way forward for the next generation, and the installation will illuminate that vision from the perspective of the next generation of designers."
Barnes is principal of his firm Studio Barnes and is assistant professor and director of the Community Housing and Identity Lab (CHIL) at the University of Miami.
Lexus is the official automotive partner of Design Miami, the collectable design fair that takes place alongside the Art Basel/Miami art fair in Miami Beach this week.
ON/ will be on show from 1 to 5 December at Design Miami, which takes place alongside Art Basel Miami Beach and other events as part of Miami art week. See Dezeen Events Guide for an up-to-date list of architecture and design events taking place around the world.