The 155-room hotel is being developed in the pixelated King Power Mahanakhon.
Its interiors, which are being designed by Hayon in collaboration with the brand's in-house designers, are hoped to encapsulate the "unmistakable energy of the Thai capital".
"There is nothing in Bangkok, or the entire region, like what we have created here," said The Standard's executive chairman Amar Lalvani.
"We love the energy, style and culture Bangkok offers and couldn't be more proud to partner with King Power to open our flagship for the region in this awe-inspiring building, in this incredible city."
The 78-storey King Power Mahanakhon was chosen as the host building for the hotel in recognition of its iconic architectural design and setting within Bangkok's central business district.
It is also in close proximity to Bangkok’s Old Town, which the brand said: "has recently become the chosen enclave for the city's dynamic creative community".
The interiors of the hotel will be distinguished by bright colours and fluid shapes. There will also be a mix of art installations and greenery.
These finishes have been developed by Hayon to challenge the usual aesthetic of other luxury hotels in Bangkok.
Hotel rooms will range in size from 40-square-metre guest rooms to a spacious 144-square-metre penthouse.
In addition to the hotel rooms will be a meeting and events room, as well as shops and a gym that will be open to the local community.
Like all other hotels by The Standard, there will also be an outdoor terrace pool and a mix of restaurant, lounge, bar and nightlife venues.
The terrace, described by The Standard as "the highest alfresco sky beach in Bangkok" will have sweeping views of the city.
The Standard was established in 1999. It is known for its design-led approach to hotels.
Its Bangkok outpost joins the US and European flagships, named The Standard, High Line, and The Standard, London, as well as waterside retreats in Miami, the Maldives, and Hua Hin. The Standard, Ibiza is also opening this spring.
To celebrate the opening of The Standard, Bangkok Mahanakhon, the brand is offering a pre-opening discount of 25 per cent on bookings until 31 Jul 2022 for stays until 28 Feb 2023.
For more information on The Standard, Bangkok Mahanakhon, and its opening, visit its website.
The imagery is courtesy of The Standard.
This article was written for The Standard as part of a partnership. Find out more about Dezeen partnership content here.