Frank Lloyd Wright at 150: Unpacking the Archive will open next summer and comprise approximately 450 works created over his 60-year career.
Wright is considered one of the 20th century's most important architects, and his work credited a precursor to the Modernism movement.
"Wright was one of the most prolific and renowned architects of the 20th century, a radical designer and intellectual who embraced new technologies and materials, pioneered do-it-yourself construction systems as well as avant-garde experimentation, and advanced original theories with regards to nature, urban planning, and social politics," said the museum.
Born in June 1867 in Wisconsin, Wright started out working under architects Joseph Lyman Silsbee then Louis Sullivan in Chicago, and established his own practice in the city in 1893.
He went on to lead the Prairie School movement, which straddled the turn of the 20th century and was prolific in the American Midwest. It was characterised by low, horizontal roof lines and overhanging eaves – designed in response to the area's flat landscape.
Among his most famous later projects are the 1927 Fallingwater house in Pennsylvania, the 1939 Johnson Wax headquarters in Wisconsin and the 1959 Guggenheim Museum in New York. Last year, 10 of his buildings were nominated for UNESCO's World Heritage List.
MoMa's exhibition will be divided into sections, each based around a key item or cluster of objects from the Frank Lloyd Wright archives.
These will include architectural drawings, models, building fragments, films, television broadcasts and print media, along with furniture, tableware, textiles, paintings, photographs and scrapbooks.
A selection of the works will be on view to the public for the first time.
"The exhibition seeks to open up Wright's work to critical inquiry and debate, and to introduce experts and general audiences alike to new angles and interpretations of this extraordinary architect," said MoMA.
Frank Lloyd Wright at 150 will run from 12 June to 1 October 2017.
MoMA is currently hosting a showcase of contemporary Japanese architecture. It has announced an exhibition of projects that tackle the issue of shelter for global refugee emergencies to open in autumn 2016.
Earlier this year, speculation arose that the institution was closing its architecture and design galleries, but MoMA stated that it has no plans to axe these dedicated spaces after renovation of its Midtown building completes.