"The location has significance locally with a history marked by trading, transport, riots and landmark pubs, and is now at the centre of Brixton's resurgence as a cultural hotspot," said the designers.
"The crossing has a high volume of cars, cyclists and pedestrians and can be a precarious place to navigate."
To make the crossing more visible to both pedestrians and drivers, Eley Kishimoto's 90s-inspired Flash pattern was applied to the floor in bold white, yellow, green and red colours.
The project is similar to one recently completed by artist Camille Walala, who applied her signature graphic patterns to a pedestrian crossing in Bankside, south London.
Other events taking place across the capital include an exhibition of poo-related designs and an a retail installation inspired by the 1960s Op Art movement.