The limited edition sneakers were created by The Shoe Surgeon, whose real name is Dominic Ciambrone, to mark the launch of the beer brand's Heineken Silver beer.
In total 32 pairs of trainers were made with transparent soles filled with Heineken Silver allowing users to "walk on beer".
The beer was injected into the sole using a surgical method so the alcohol is securely trapped, while a transparent tube that runs across the upper exterior of the shoe is also filled with beer.
According to Heineken, the sole was designed to create a smooth walking experience that mirrors the smooth taste of Heineken Silver.
"Partnering with Heineken for their new beer was a fun challenge," said Ciambrone. "We both share a passion for innovation and pushing boundaries and created a design to reflect that."
"The shoe not only embodies the energy of Heineken Silver but literally carries it," he continued.
The custom sneakers also include design elements informed by the appearance of Heineken's beer bottle. Its exterior features its colourways – red, green and silver – while the laces and interior are red.
The tongue of the shoe includes a removable metal bottle opener, which allows users to enjoy a beverage "whenever the occasion arises".
"Heineken has always been passionate about brewing innovation that aligns with the culture and taste profile of drinkers," said Heineken brand director Rajeev Sathyesh.
"Heineken Silver does just that, with a smooth and perfectly balanced taste profile that matches the more informal social occasions of today," he continued. "Being able to represent that through an exclusive collaboration with The Shoe Surgeon is a fantastic project and a great manifestation of the purpose of Heineken Silver."
Ciambrone is known for creating unusual sneakers and his clients include musicians LeBron James, DJ Khaled and Drake.
More sneaker designs include HySpeed trainers by McLaren and Athletic Propulsion Labs that are informed by the brand's supercar design and Satan Shoes by American musician Lil Nas X and Brooklyn brand MSCHF, which were customised with human blood.