Bidders can vie for 40 pieces – many of which are unique or limited editions – from lighting designers Lindsey Adelman and Apparatus, artist Misha Kahn, design store The Future Perfect, and many more. The total haul is valued at almost $100,000 (£800,000).
"The auction will also serve as a public statement that Design for Progress and its supporters demand fair and ethical governance and refuse to support intolerance, discrimination, or regression," said the organisers.
The two-week auction opened yesterday and closes 7 April 2017.
It follows an earlier online fundraiser launched in response Trump's victory in the US presidential election last year, during which $20,000 was raised for seven groups and organisations that support groups and issues likely to be affected by his policies.
"Design for Progress was launched by the editors of Sight Unseen the day after the election in November, as a call to action for the design community to rally behind progressive causes and vulnerable groups most in need of support under the current administration," the organisers said.
Sight Unseen was launched by journalists Monica Khemserov and Jill Singer in 2009. The digital magazine has also organised the annual Sight Unseen Offsite exhibition during the NYCxDesign festival each May since 2014.