The futuristic boots curve up and around the leg, encompassing the lower leg on both sides and looping behind the knee.
A long seam runs up the front of the upper before it opens at the top, while the back of the calf is left exposed.
Seven-inch-high heels cantilever from the back of the solid base, which continues the shape of the upper to the ground.
A peep-toe boot was also created in a similar style, but with a strap that wraps around the leg at ankle height instead of at the knee.
Black, cream and white leather was used for the designs, complimenting the colours of Van Herpen's garments.
The Biopiracy collection was shown on Tuesday during Paris Fashion Week.
This is the ninth time United Nude and Van Herpen have worked together on footwear for her shows. "Working with Iris Van Herpen is each time a big challenge for us as she pushes boundaries with ideas for things that have never been done before," said United Nude founder Rem D Koolhaas.
Last season they created 3D-printed shoes the resembled tree roots and the year before they added spikes made from semi-precious stones within the heels of platforms.
Dezeen interviewed Koolhaas last year, when he discussed United Nude's "extreme theatre" shoe collaborations and talked about the future of 3D-printed footwear.
Here's some information from Iris Van Herpen and United Nude:
United Nude make shoes with Iris Van Herpen for her Biopiracy collection
United Nude collaborates with Iris Van Herpen for shoes completing her collection for its 9th consecutive time. Nevertheless this is the first time that two instead of just one design graced the runway, in the form of the Biopiracy Boot and the Biopiracy peeptoe ankle Bootie, both on staggering 7 inch tall platform cantilevered heels.
The Biopiracy collection by Iris Van Herpen emerged from astonishment of companies’ patented human genes. As part of the show, Lawrence Malstaf created art installations, which developed the impression of models being weightless and breathless. In their half-sleep they seem bio-hacked, to slow down time and energy. Iris van Herpen and Lawrence Malstaf experiment with living objects, kinetic architecture and physical interaction through fashion in installation art.
A 3D printing collaboration with Julia Koerner and Materialise fuses the artisanal with the technical to create a kinetic dress which dances as it amplifies bodily movement. The Iris Van Herpen × United Nude Boot overrules the natural shape of the foot; this makes the graphically leather moulded boots futuristic sculptures extending the legs with a new silhouette into motion. Iris Van Herpen and United Nude is a match made in heaven from day one, as they are both not afraid of breaking boundaries by experimentation with design and technology.
Rem D Koolhaas: "Working with Iris Van Herpen is each time a big challenge for us as she pushes boundaries with ideas for things that have never been done before. Collaboration partners like Iris Van Herpen and Zaha Hadid give us way for our continuation in re-inventing shoes. United Nude was originally founded on this principle with our sculptural sandals just over ten years ago; breaking the rules of conventional ladies shoe-making, not for the sake if breaking them, but simply by not knowing them."