In its announcement, the London institution credited Brody with "remodelling and evolving" the School of Communication's programmes, which now include animation, digital direction, information experience design and visual communication.
"Professor Brody has been dean since August 2011 and, in that time, has successfully remodelled and evolved all programmes within the School of Communication, as well as introducing new and innovative teaching method," said the statement.
"He has launched information experience design (IED) and digital direction as two new additions to the college's portfolio and contributed vision and insight to the college's strategic thinking and branding."
After seven years in the role, Brody said he felt now was the "right moment" for him to step aside to allow a new dean to take the school into its next phase of development.
However, he will continue his association with the RCA as a professor of visual communication.
"I am delighted that professor Brody has agreed to continue his association with the Royal College of Art in a new role of professor of visual communication, thereby maintaining his strong link with the vision and work of the RCA and continuing to contribute to the College's world-class research strengths and industry partnerships," said deputy vice-chancellor and provost Naren Barfield.
Brody is known for his pioneering work in the late 80s and 90s as the designer behind influential magazine The Face. In more recent years, he has created the new visual identity for UK broadcaster Channel 4 and the typeface for England 2014 football kit.
He also reworked the Royal College of Art's house font by Margaret Calvert as part of the London institution's rebrand in 2012, and designed Coca-Cola's first ever own-brand typeface
Since becoming a dean of the Royal College of Art's School of Communication, he has spoken out against government plans to remove creative subjects from the UK curriculum, and also suggested that the design industry in the UK should step in to plug the education funding gap.