Ottolenghi Chelsea features bare plaster walls, pink terrazzo tiles, red upholstered seating and rattan seats.
The look is a departure from the other Ottolenghi delis, where the design is typically more bright and minimal.
Meitlis has been behind the design of all the other delis, as well as sister restaurants Nopi and Rovi, which all feature the food of Israeli chef Yotam Ottolenghi and business partners Noam Bar and Sami Tamimi.
Here the idea was to make more of a statement, using colours that match the Ottolenghi tableware collection recently launched by Serax.
In the same spirit, the shopfront and exterior signage bring in vibrant shades of yellow, blue and turquoise.
"I take my approach from looking very closely at Yotam's approach to his food," said Meitlis, who has studios both in London and Tel Aviv.
"It's about taking very basic ingredients but using them in a slightly different way."
The clay plaster on the walls was made using recycled bricks, which provide the warm terracotta colour.
The multi-tonal character of this material is emphasised by curving walls that offer a play of light and shadow.
Meitlis worked with artist Ivo Bisignano – who also designed the tableware collection – to create the restaurant's distinctive floor, where pink terrazzo alternates with white tiles to create a striped effect.
The same terrazzo also features on wall surfaces at the front of the space and behind the deli counter.
The upholstered banquettes bring a geometric element to the design, combining blocky seats with cylindrical cushions. The choice of red fabric allows these to become the most eye-catching elements in the space.
They are paired with white circular tables and Mies van der Rohe-designed MR Chairs, which introduce more curves.
Other elements include the familiar deli counter, where the cakes, pastries and salads create an appetising display.
"We usually start from scratch; almost all elements of the design are made specifically," Meitlis told Dezeen. "The only items we bought were the iconic Mies chairs."
"Once again, it's about mirroring the brand's attitude; all the food is made in the kitchen, with few elements pre-prepared."
Ottolenghi Chelsea opened in January 2022 and is located on Pavilion Road, in a converted Victorian stable building that is now home to various independent retail brands.
Dishes for Ottolenghi delis and restaurants are developed at the brand's test kitchen in Holloway, which was recently overhauled by Studiomama with pops of saffron yellow and raspberry red.